NOD1 Effector Reporter Cell
CBP74531
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
| NOD1（Nucleotide-binding oligomerization domain-containing protein 1，核苷酸結(jié)合寡聚化結(jié)構(gòu)域蛋白1）是固有免疫系統(tǒng)中的一種重要的胞內(nèi)模式識別受體（PRR），主要識別細(xì)菌細(xì)胞壁成分——主要是革蘭氏陰性菌肽聚糖中的γ-谷氨酰-二氨基庚二酸（iE-DAP）。 | |
| II. Description | |
| NOD1 Effector Reporter Cell報告基因藥靶模型很好的模擬了體內(nèi) NOD1 的信號轉(zhuǎn)導(dǎo)過程。 | |
| III. Introduction | |
| Expressed gene: | NOD1 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | MEM + 10%FBS +1% NEAA + 1mM NaP + 1μg/ml Puromycin + 100 μg/ml Hygromycin B |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| IV. Representative Data | |
 Figure 1. Dose Response of TriDAP Dihydrochloride in NOD1 Effector Reporter Cell(C50). |
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